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-- -- -- -- the -- -- -- -- -- -- -- -- -- -- -- press the escape key to close the dialog menu. menu -- tabs in this tab group open the tab panel widget in a dialog. once a tab is interacted with, press the escape key to exit the dialog and return to the page content. menu search news & events close search apply visit see programs close home our science home page mitochondrial gene expression preventing mitochondrial disease transmission clinical mitochondrial disease clinical research neuropathology treatments mitochondria in common disease seminars young scientists career support patient and public what are mitochondria? energy conversion what do mitochondria look like? mitochondrial dna different dna about our clinic general information about mitochondrial disease diagnosis monitoring operations holidays exercise employment education drug information driving diet alcohol information for women specific conditions large-scale mitochondrial dna deletions neurogenic weakness, ataxia, and retinitis pigmentosa (narp) multiple mitochondrial dna deletions mitochondrial neuro-gastro-intestinal encephalopathy (mngie) myoclonic epilepsy and ragged red fibres (merrf 8344 a>g) mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (melas) 3243 a>g mutation leigh syndrome mitochondrial dna depletion syndrome (mdds) alpers disease our patient days mitonews fundraising clinical professionals clinical team members clinical services diagnostic laboratory newcastle mitochondrial ncg lab referral form newcastle mitochondrial ncg lab user manual newcastle mitochondrial ncg lab tarriffs clinical publications clinical guidelines nmdas m.3243a>g heteroplasmy tool clinical guidelines mitochondrial patient cohort engagement patient engagement our patient days lily family day mitochondrial donation mitochondrial research matters nihr ok to ask campaign great north childrens hospital birthday mitonews public engagement newcastle university fms festive lecture 2016 royal society pairing scheme the art of mitochondrial biology impact matters mitochondria matters keeping active matters genetics matters events school engagement mini med school nuffield foundation student placements north east digital event seven stories big ideas event leading edge museum events working together engagement examples useful engagement links team members principle investigators professor zofia chrzanowska-lightowlers professor mary herbert prof rita horvath professor robert lightowlers professor robert mcfarland prof robert taylor prof sir doug turnbull post doctoral scientists clinical team members associated researchers nhs diagnostic laboratory team members post graduate students administrative and technical contact us close recent news mtdna heteroplasmy level and copy number in mitochondrial disease june 4, 2018 wellcome centre for mitochondrial research – phd studentships january 3, 2018 research associate positions december 6, 2017 more news upcoming events valence exhibit and symposium exhibit 20-30 september 2017 with a symposium on the 27th september 2017 prof. mary herbert tedmed talk 1-3 november 2017 human mitochondrial translation machinery talk 28th june, 10-11 am more events twitter facebook youtube -- you are using an outdated browser. please upgrade your browser to improve your experience. the wellcome trust centre for mitochondrial research is built on our long standing clinical and scientific expertise in mitochondrial disease. we are totally committed to provide the best of care for our patients and this means that we must understand more about the mechanisms underlying mitochondrial disease. if we are to develop new strategies for preventing or treating mitochondrial disease it is fundamentally dependent upon very high quality research. to learn more please scroll down or click on one of the menu options to the right. -- the wellcome trust centre for mitochondrial research is built on our long standing expertise in mitochondrial disease. it is based within the medical school of newcastle university. a huge breadth of research is undertaken within our centre to address questions regarding mitochondrial disease. our aim is to transform the lives of patients with mitochondrial disease the wellcome centre for mitochondrial research is built on our long standing expertise in mitochondrial disease -- our centre the wellcome centre for mitochondrial research is based within the medical school of newcastle university. our research a huge breadth of research is undertaken within our centre to address questions regarding mitochondrial disease. our medicine we offer expert advice on clinical management at a leading internationally renowned centre for mitochondrial disease. your science we are committed to effectively engaging with our patients and the public, putting our patients at the heart of everything we do. their future we work together with patients to improve and transform the lives of patients, their carers and future generations. " "we are dedicated to providing the best possible clinical care supported by world class research" . name dr robert mcfarland clinical senior lecturer and consultant paediatric neurologist " "there is such a wealth of knowledge and enthusiasm for the research being done." name hannah rosa title phd student divisions our research -- our research " "researchers at wcmr have access to a range of amazing advanced technologies" name christie waddington class of phd student " "findings from the mitochondrial patient cohort study are shaping the standard of patient care" name yi ng title clinical research associate and honorary neurology registrar " "engagement is an important part of a researchers job and probably one of the most enjoyable parts" name amy vincent class of phd student -- tweets by @mitoresearch newcastle university 4th floor cookson building medical school framlington place newcastle upon tyne ne2 4hh 0191 208 3084 twitter facebook youtube search home seminars about our clinic our science contact us privacy policy twelve eleven ten nine eight seven six six five four four four three three three three one one one one one one one one one one one one -- -- -- '); } press the escape key to close the dialog. close the mitochondrial network — the mitochondrial network: image of a u2os cell with mitochondria stained by 5nm tmrm (a fluorescent dye that accumulates in mitochondria due to the membrane potential) and visualized by fluorescence microscopy. image by dr. kyle thompson. mitochondria in mouse small intestine — green staining is cox i, red staining is beta catenine. this biopsy highlights cox i deficiency and tumour formation. image by dr laura greaves mitochondria within the cerebellum — human cerebellum control tissue showing the purkunjie cells. section stained with neurofilament marker, a marker of filament protein in axons (green) and porin a marker of mitochondria. (red) image by dr jonathan phillips. confocal image of a preimplantation stage mouse embryo — confocal image of a preimplantation stage mouse embryo approximately 3.5 days after fertilisation. at this stage of development, the embryo is a bundle of cells known as an early blastocyst and is approximately 80 microns in diameter. this blastocyst has been labelled with two dyes that allow individual cells within the embryo to be visualized. these dyes stain the nucleus of each cell (dapi; blue) and the membrane that surrounds each cell (alexa fluor phalloidin; red). a series of optical sections have been reconstructed and rendered to form the 3d image (with the help of dr. alex laude newcastle university bioimaging). mitochondria in brain arteriole — sub title immunofluorescent labelling of a brain arteriole (blue) from a patient with m.3243a>g mutation showing mitochondria (red) and mitochondrial proteins (green). the arteriole shows abnormally aggregated mitochondria in the vessel wall which are lacking key mitochondrial protein suggesting respiratory chain deficiency. image by dr nichola lax. mitochondria in mouse cerebellum tissue — image of mouse cerebellum tissue stained for dapi (blue), cox i (green), neurofilament h (red) myelin basic protein (purple) image by dr jonathan phillips. mitochondria in human muscle tissue — image of muscle tissue of a patient with multiple mtdna deletions. this image is an overlay of porin (red), laminin (white), cox-i (green) and ndufb8 (purple). image by dr. marianna rocha. a fertilised egg undergoing the mitochondrial donation technique — the egg has had its own nucleus (containing the nuclear dna) removed and is waiting for the nucleus from a different egg to be inserted. the egg is being held in place using the glass needle that can be seen on the left of the image. the nucleus from the other egg will be inserted into this egg using the glass needle seen on the right of the image. image provided by dr lyndsey butterworth. human cerebellum tissue section — human cerebellum tissue section stained with neurofilament h (green) myelin basic protein (red), and cox i (purple) image by dr jonathan phillips. mitochondria within a brain arteriole — immunofluorescent labelling of a brain arteriole (blue) from a patient with m.3243a>g mutation showing mitochondria (red) and mitochondrial proteins (green). the arteriole shows abnormally aggregated mitochondria in the vessel wall which are lacking key mitochondrial protein suggesting respiratory chain deficiency. image by dr nichola lax. mouse cerebellum tissue — mouse cerebellum tissue stained for dapi (blue), cox i (green), neurofilament h (red) myelin basic protein (purple) image by dr jonathan phillips. human cerebellum control tissue section — human cerebellum control tissue section stained with neurofilament h, (blue) ndufa13 (red), and myelin basic protein (purple) image by dr jonathan phillips.

URL analysis for newcastle-mitochondria.com

http://www.newcastle-mitochondria.com/patient-and-public-home-page/mitochondria-heteroplasmy/
http://www.newcastle-mitochondria.com/engagement/
http://www.newcastle-mitochondria.com/our-science-home-page/mitochondria-in-common-disease/
http://www.newcastle-mitochondria.com/patient-and-public-home-page/fundraising/
http://www.newcastle-mitochondria.com/patient-and-public-home-page/diet/
http://www.newcastle-mitochondria.com/m-3243ag-heteroplasmy-tool/
http://www.newcastle-mitochondria.com/patient-and-public-home-page/driving/
http://www.newcastle-mitochondria.com/dr-robert-mcfarland/
http://www.newcastle-mitochondria.com/patient-and-public-home-page/monitoring/
http://www.newcastle-mitochondria.com/our-science-home-page/associated-researchers/
http://www.newcastle-mitochondria.com/clinical-team-members/
http://www.newcastle-mitochondria.com/our-science-home-page/administrative-and-technical/
http://www.newcastle-mitochondria.com/academics/index.html
http://www.newcastle-mitochondria.com/patient-engagement/
http://www.newcastle-mitochondria.com/#menu

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Domain Name: NEWCASTLE-MITOCHONDRIA.COM
Registry Domain ID: 1743331770_DOMAIN_COM-VRSN
Registrar WHOIS Server: whois.1and1.com
Registrar URL: http://registrar.1and1.info
Updated Date: 2016-09-08T07:16:58Z
Creation Date: 2012-09-07T14:57:02Z
Registry Expiry Date: 2017-09-07T14:57:02Z
Registrar: 1&1 Internet SE
Registrar IANA ID: 83
Registrar Abuse Contact Email: [email protected]
Registrar Abuse Contact Phone: +1.6105601459
Domain Status: clientTransferProhibited https://icann.org/epp#clientTransferProhibited
Name Server: NS67.1AND1.CO.UK
Name Server: NS68.1AND1.CO.UK
DNSSEC: unsigned
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  REGISTRAR 1&1 Internet SE

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  SERVER com.whois-servers.net

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  PORT 43

  TYPE domain

DOMAIN

  NAME newcastle-mitochondria.com

  CHANGED 2016-09-08

  CREATED 2012-09-07

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  NS67.1AND1.CO.UK 217.160.80.173

  NS68.1AND1.CO.UK 217.160.81.173

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